Mumps おたふくかぜ、流行性耳下腺炎

 

 

• Mumps virus 

  • Family – paramyxoviridae
• Structure
  • Viral polymerase
  • Single-stranded RNA
  • Phospholipid bilayer
• Surface
  • Hemagglutinin neuraminidase
  • Fusion
• Multinucleated giant cell AKA Syncytium
• S&S
  • Parotid salivary glands (Parotitis) 耳下腺炎
    • swelling
    • Ear ache
    • Trismus
      • spasms of chewing muscle
  • CNS
    • Meningitis
    • Encephalitis
  • Headache
  • Difficulty balance
  • Hearing loss
  • Testicles
    • Orchitis 睾丸(こうがん)炎
  • Epididymides
    • Epididymitis 副睾丸炎
  • Glumerulonephritis
    • Hematuria
    • Protenuria
• Diagnosis
  • Antibody titer
    • 抗体価